node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24652.1 | AGE24654.1 | H045_02880 | H045_02890 | COG4807 Uncharacterized protein conserved in bacteria. | GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | 0.530 |
AGE24652.1 | lepB | H045_02880 | H045_02240 | COG4807 Uncharacterized protein conserved in bacteria. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.400 |
AGE24652.1 | parC | H045_02880 | H045_23355 | COG4807 Uncharacterized protein conserved in bacteria. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.416 |
AGE24652.1 | rimO | H045_02880 | H045_02895 | COG4807 Uncharacterized protein conserved in bacteria. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.628 |
AGE24654.1 | AGE24652.1 | H045_02890 | H045_02880 | GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | COG4807 Uncharacterized protein conserved in bacteria. | 0.530 |
AGE24654.1 | rimO | H045_02890 | H045_02895 | GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.599 |
AGE26404.1 | rimO | H045_11695 | H045_02895 | COG3038 Cytochrome B561. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.695 |
kup | rimO | H045_02900 | H045_02895 | Low affinity potassium transporter protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.483 |
lepB | AGE24652.1 | H045_02240 | H045_02880 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | COG4807 Uncharacterized protein conserved in bacteria. | 0.400 |
lepB | parC | H045_02240 | H045_23355 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.684 |
lepB | ribD | H045_02240 | H045_17750 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.497 |
lepB | rimO | H045_02240 | H045_02895 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.555 |
parC | AGE24652.1 | H045_23355 | H045_02880 | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | COG4807 Uncharacterized protein conserved in bacteria. | 0.416 |
parC | lepB | H045_23355 | H045_02240 | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.684 |
parC | rimO | H045_23355 | H045_02895 | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.516 |
prfA | rimO | H045_00515 | H045_02895 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.483 |
ribD | lepB | H045_17750 | H045_02240 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.497 |
ribD | rimO | H045_17750 | H045_02895 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.582 |
ribD | rlmN | H045_17750 | H045_16170 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.545 |
rimO | AGE24652.1 | H045_02895 | H045_02880 | Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | COG4807 Uncharacterized protein conserved in bacteria. | 0.628 |