node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24694.1 | AGE24938.1 | H045_03090 | H045_04310 | Hypothetical protein. | Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.679 |
AGE24694.1 | AGE24940.1 | H045_03090 | H045_04320 | Hypothetical protein. | COG1309 Transcriptional regulator. | 0.440 |
AGE24694.1 | AGE25730.1 | H045_03090 | H045_08300 | Hypothetical protein. | Hypothetical protein; COG0464 ATPases of the AAA+ class. | 0.700 |
AGE24694.1 | AGE25772.1 | H045_03090 | H045_08510 | Hypothetical protein. | Putative regulatory protein. | 0.704 |
AGE24694.1 | AGE27179.1 | H045_03090 | H045_15570 | Hypothetical protein. | Putative transcriptional regulator. | 0.735 |
AGE24938.1 | AGE24694.1 | H045_04310 | H045_03090 | Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Hypothetical protein. | 0.679 |
AGE24938.1 | AGE24940.1 | H045_04310 | H045_04320 | Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | COG1309 Transcriptional regulator. | 0.484 |
AGE24938.1 | lexA | H045_04310 | H045_04315 | Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.889 |
AGE24940.1 | AGE24694.1 | H045_04320 | H045_03090 | COG1309 Transcriptional regulator. | Hypothetical protein. | 0.440 |
AGE24940.1 | AGE24938.1 | H045_04320 | H045_04310 | COG1309 Transcriptional regulator. | Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.484 |
AGE24940.1 | AGE25730.1 | H045_04320 | H045_08300 | COG1309 Transcriptional regulator. | Hypothetical protein; COG0464 ATPases of the AAA+ class. | 0.426 |
AGE24940.1 | AGE25772.1 | H045_04320 | H045_08510 | COG1309 Transcriptional regulator. | Putative regulatory protein. | 0.429 |
AGE24940.1 | AGE25904.1 | H045_04320 | H045_09170 | COG1309 Transcriptional regulator. | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.416 |
AGE24940.1 | AGE26048.1 | H045_04320 | H045_09905 | COG1309 Transcriptional regulator. | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.416 |
AGE24940.1 | AGE26797.1 | H045_04320 | H045_13660 | COG1309 Transcriptional regulator. | COG3198 Uncharacterized protein conserved in bacteria. | 0.488 |
AGE24940.1 | AGE27179.1 | H045_04320 | H045_15570 | COG1309 Transcriptional regulator. | Putative transcriptional regulator. | 0.460 |
AGE24940.1 | lexA | H045_04320 | H045_04315 | COG1309 Transcriptional regulator. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.486 |
AGE24940.1 | nagZ | H045_04320 | H045_04325 | COG1309 Transcriptional regulator. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.530 |
AGE25730.1 | AGE24694.1 | H045_08300 | H045_03090 | Hypothetical protein; COG0464 ATPases of the AAA+ class. | Hypothetical protein. | 0.700 |
AGE25730.1 | AGE24940.1 | H045_08300 | H045_04320 | Hypothetical protein; COG0464 ATPases of the AAA+ class. | COG1309 Transcriptional regulator. | 0.426 |