STRINGSTRING
AGE25110.1 AGE25110.1 AGE25109.1 AGE25109.1 ccmI ccmI ccmC ccmC AGE25111.1 AGE25111.1 ccmE ccmE ccmB ccmB dsbD dsbD ccmD ccmD ccmA ccmA AGE25113.1 AGE25113.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
AGE25110.1Cytochrome C biogenesis, thiol:disulfide interchange protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (178 aa)    
Predicted Functional Partners:
AGE25109.1
Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor.
 
  
 0.991
ccmI
COG4235 Cytochrome c biogenesis factor.
 
  
 0.980
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.979
AGE25111.1
Cytochrome c-type biogenesis protein CycL; Possible subunit of a heme lyase.
 
  
 0.979
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.977
ccmB
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.930
dsbD
Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.907
ccmD
Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
  
 0.894
ccmA
Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.890
AGE25113.1
Lipoprotein.
       0.763
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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