STRINGSTRING
AGE25239.1 AGE25239.1 AGE25241.1 AGE25241.1 AGE25242.1 AGE25242.1 AGE25243.1 AGE25243.1 AGE25240.1 AGE25240.1 hisZ hisZ AGE25244.1 AGE25244.1 hisF hisF hisH hisH hisB hisB hisI hisI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AGE25239.1Hypothetical protein; COG0560 Phosphoserine phosphatase. (217 aa)    
Predicted Functional Partners:
AGE25241.1
Putative ABC transporter membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.
 
    0.821
AGE25242.1
Putative ABC transporter membrane protein; COG4132 ABC-type uncharacterized transport system, permease component.
 
    0.797
AGE25243.1
COG1524 Uncharacterized proteins of the AP superfamily.
 
     0.775
AGE25240.1
Putative ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.
  
    0.718
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
 
    0.585
AGE25244.1
ABC transporter periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.
 
     0.566
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.526
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.511
hisB
COG0131 Imidazoleglycerol-phosphate dehydratase.
  
  
 0.496
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.494
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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