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acnB acnB AGE26311.1 AGE26311.1 gltA gltA AGE26312.1 AGE26312.1 acnA acnA prpB prpB AGE26320.1 AGE26320.1 prpF prpF AGE26875.1 AGE26875.1 sucC sucC AGE27191.1 AGE27191.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family. (869 aa)    
Predicted Functional Partners:
AGE26311.1
COG0538 Isocitrate dehydrogenases.
  
 
 0.977
gltA
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.968
AGE26312.1
COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
 
 0.943
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.926
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.917
AGE26320.1
COG2224 Isocitrate lyase.
     
 0.916
prpF
COG2828 Uncharacterized protein conserved in bacteria.
    
 0.916
AGE26875.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.843
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.811
AGE27191.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.794
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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