node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24519.1 | AGE27635.1 | H045_02215 | H045_17865 | COG2927 DNA polymerase III, chi subunit. | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.850 |
AGE24519.1 | AGE28270.1 | H045_02215 | H045_21040 | COG2927 DNA polymerase III, chi subunit. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.963 |
AGE24519.1 | dnaE2 | H045_02215 | H045_10880 | COG2927 DNA polymerase III, chi subunit. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.770 |
AGE24519.1 | dnaQ | H045_02215 | H045_06910 | COG2927 DNA polymerase III, chi subunit. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.944 |
AGE24519.1 | dnaX | H045_02215 | H045_13715 | COG2927 DNA polymerase III, chi subunit. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.988 |
AGE24519.1 | holA | H045_02215 | H045_17455 | COG2927 DNA polymerase III, chi subunit. | COG1466 DNA polymerase III, delta subunit. | 0.991 |
AGE24519.1 | holB | H045_02215 | H045_14565 | COG2927 DNA polymerase III, chi subunit. | DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. | 0.990 |
AGE26242.1 | AGE26243.1 | H045_10885 | H045_10890 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | Hypothetical protein; COG0468 RecA/RadA recombinase. | 0.995 |
AGE26242.1 | AGE28270.1 | H045_10885 | H045_21040 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.851 |
AGE26242.1 | dnaE2 | H045_10885 | H045_10880 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.972 |
AGE26242.1 | holB | H045_10885 | H045_14565 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. | 0.536 |
AGE26242.1 | lexA-2 | H045_10885 | H045_10895 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.904 |
AGE26243.1 | AGE26242.1 | H045_10890 | H045_10885 | Hypothetical protein; COG0468 RecA/RadA recombinase. | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | 0.995 |
AGE26243.1 | dnaE2 | H045_10890 | H045_10880 | Hypothetical protein; COG0468 RecA/RadA recombinase. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.969 |
AGE26243.1 | lexA-2 | H045_10890 | H045_10895 | Hypothetical protein; COG0468 RecA/RadA recombinase. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.873 |
AGE27635.1 | AGE24519.1 | H045_17865 | H045_02215 | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | COG2927 DNA polymerase III, chi subunit. | 0.850 |
AGE27635.1 | AGE28270.1 | H045_17865 | H045_21040 | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.643 |
AGE27635.1 | dnaE2 | H045_17865 | H045_10880 | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.777 |
AGE27635.1 | dnaX | H045_17865 | H045_13715 | Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.897 |
AGE28270.1 | AGE24519.1 | H045_21040 | H045_02215 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG2927 DNA polymerase III, chi subunit. | 0.963 |