node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE25265.1 | AGE26242.1 | H045_05955 | H045_10885 | COG0417 DNA polymerase elongation subunit (family B). | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | 0.833 |
AGE25265.1 | AGE28270.1 | H045_05955 | H045_21040 | COG0417 DNA polymerase elongation subunit (family B). | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.985 |
AGE25265.1 | lexA | H045_05955 | H045_04315 | COG0417 DNA polymerase elongation subunit (family B). | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.416 |
AGE25265.1 | ligD | H045_05955 | H045_08195 | COG0417 DNA polymerase elongation subunit (family B). | ATP-dependent DNA ligase; COG0708 Exonuclease III. | 0.673 |
AGE25265.1 | polA | H045_05955 | H045_21470 | COG0417 DNA polymerase elongation subunit (family B). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.983 |
AGE25265.1 | recA | H045_05955 | H045_02830 | COG0417 DNA polymerase elongation subunit (family B). | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.777 |
AGE25903.1 | AGE26242.1 | H045_09165 | H045_10885 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | 0.580 |
AGE25903.1 | polA | H045_09165 | H045_21470 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.682 |
AGE25903.1 | recA | H045_09165 | H045_02830 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.738 |
AGE26242.1 | AGE25265.1 | H045_10885 | H045_05955 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | COG0417 DNA polymerase elongation subunit (family B). | 0.833 |
AGE26242.1 | AGE25903.1 | H045_10885 | H045_09165 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.580 |
AGE26242.1 | AGE26243.1 | H045_10885 | H045_10890 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | Hypothetical protein; COG0468 RecA/RadA recombinase. | 0.995 |
AGE26242.1 | AGE28270.1 | H045_10885 | H045_21040 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.851 |
AGE26242.1 | dnaE2 | H045_10885 | H045_10880 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.972 |
AGE26242.1 | lexA | H045_10885 | H045_04315 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.598 |
AGE26242.1 | lexA-2 | H045_10885 | H045_10895 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.904 |
AGE26242.1 | ligD | H045_10885 | H045_08195 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | ATP-dependent DNA ligase; COG0708 Exonuclease III. | 0.588 |
AGE26242.1 | polA | H045_10885 | H045_21470 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.684 |
AGE26242.1 | recA | H045_10885 | H045_02830 | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.666 |
AGE26243.1 | AGE26242.1 | H045_10890 | H045_10885 | Hypothetical protein; COG0468 RecA/RadA recombinase. | Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. | 0.995 |