node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24449.1 | AGE25081.1 | H045_01865 | H045_05025 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.908 |
AGE24449.1 | AGE26440.1 | H045_01865 | H045_11875 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 3-methyl-2-oxobutanoate dehydrogenase subunit alpha; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.965 |
AGE24449.1 | AGE26441.1 | H045_01865 | H045_11880 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 2-oxoisovalerate dehydrogenase E1 subunit beta; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. | 0.953 |
AGE24449.1 | AGE26444.1 | H045_01865 | H045_11895 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.931 |
AGE24449.1 | AGE27237.1 | H045_01865 | H045_15860 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | COG0460 Homoserine dehydrogenase. | 0.805 |
AGE24449.1 | ilvD | H045_01865 | H045_19400 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.917 |
AGE24449.1 | leuA | H045_01865 | H045_16120 | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.916 |
AGE25081.1 | AGE24449.1 | H045_05025 | H045_01865 | Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.908 |
AGE25081.1 | AGE26444.1 | H045_05025 | H045_11895 | Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.908 |
AGE25081.1 | AGE27237.1 | H045_05025 | H045_15860 | Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG0460 Homoserine dehydrogenase. | 0.450 |
AGE25081.1 | ilvD | H045_05025 | H045_19400 | Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.911 |
AGE25081.1 | leuA | H045_05025 | H045_16120 | Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.906 |
AGE25951.1 | AGE26440.1 | H045_09420 | H045_11875 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 3-methyl-2-oxobutanoate dehydrogenase subunit alpha; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.802 |
AGE25951.1 | AGE26441.1 | H045_09420 | H045_11880 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 2-oxoisovalerate dehydrogenase E1 subunit beta; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. | 0.812 |
AGE25951.1 | AGE26444.1 | H045_09420 | H045_11895 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.940 |
AGE25951.1 | AGE27237.1 | H045_09420 | H045_15860 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | COG0460 Homoserine dehydrogenase. | 0.924 |
AGE25951.1 | ilvA | H045_09420 | H045_19505 | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.852 |
AGE26440.1 | AGE24449.1 | H045_11875 | H045_01865 | 3-methyl-2-oxobutanoate dehydrogenase subunit alpha; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.965 |
AGE26440.1 | AGE25951.1 | H045_11875 | H045_09420 | 3-methyl-2-oxobutanoate dehydrogenase subunit alpha; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.802 |
AGE26440.1 | AGE26441.1 | H045_11875 | H045_11880 | 3-methyl-2-oxobutanoate dehydrogenase subunit alpha; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 2-oxoisovalerate dehydrogenase E1 subunit beta; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. | 0.999 |