node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE25002.1 | AGE27697.1 | H045_04630 | H045_18175 | P-protein; COG1605 Chorismate mutase. | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.960 |
AGE25002.1 | AGE28578.1 | H045_04630 | H045_22600 | P-protein; COG1605 Chorismate mutase. | COG1605 Chorismate mutase. | 0.918 |
AGE25002.1 | aroA | H045_04630 | H045_04640 | P-protein; COG1605 Chorismate mutase. | Bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.999 |
AGE25002.1 | aroA-2 | H045_04630 | H045_09960 | P-protein; COG1605 Chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.833 |
AGE25002.1 | aroB | H045_04630 | H045_22940 | P-protein; COG1605 Chorismate mutase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.677 |
AGE25002.1 | aroC | H045_04630 | H045_12680 | P-protein; COG1605 Chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.978 |
AGE25002.1 | aroE | H045_04630 | H045_21235 | P-protein; COG1605 Chorismate mutase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.726 |
AGE25002.1 | aroK | H045_04630 | H045_22935 | P-protein; COG1605 Chorismate mutase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.722 |
AGE25002.1 | pabB | H045_04630 | H045_14080 | P-protein; COG1605 Chorismate mutase. | COG0147 Anthranilate/para-aminobenzoate synthases component I. | 0.902 |
AGE25002.1 | trpE | H045_04630 | H045_18190 | P-protein; COG1605 Chorismate mutase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.964 |
AGE27697.1 | AGE25002.1 | H045_18175 | H045_04630 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | P-protein; COG1605 Chorismate mutase. | 0.960 |
AGE27697.1 | AGE28578.1 | H045_18175 | H045_22600 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG1605 Chorismate mutase. | 0.917 |
AGE27697.1 | aroA | H045_18175 | H045_04640 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.655 |
AGE27697.1 | aroA-2 | H045_18175 | H045_09960 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.571 |
AGE27697.1 | aroB | H045_18175 | H045_22940 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.772 |
AGE27697.1 | aroC | H045_18175 | H045_12680 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.966 |
AGE27697.1 | aroE | H045_18175 | H045_21235 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.628 |
AGE27697.1 | aroK | H045_18175 | H045_22935 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.602 |
AGE27697.1 | pabB | H045_18175 | H045_14080 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG0147 Anthranilate/para-aminobenzoate synthases component I. | 0.999 |
AGE27697.1 | trpE | H045_18175 | H045_18190 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |