STRINGSTRING
cobQ cobQ AGE26736.1 AGE26736.1 cobD cobD cobO cobO cobJ cobJ cobB-2 cobB-2 cobU cobU cobH cobH cobM cobM cobS cobS AGE27170.1 AGE27170.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (483 aa)    
Predicted Functional Partners:
AGE26736.1
Threonine-phosphate decarboxylase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
 
 0.997
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.996
cobO
cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.996
cobJ
COG2073 Cobalamin biosynthesis protein CbiG.
  
 0.992
cobB-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.989
cobU
Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
  
 0.971
cobH
precorrin-8X methylmutase; COG2082 Precorrin isomerase.
  
 0.968
cobM
COG2875 Precorrin-4 methylase.
 
  
 0.943
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.926
AGE27170.1
ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
  
 
 0.922
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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