node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE27602.1 | AGE27603.1 | H045_17700 | H045_17705 | DNA-binding transcriptional activator OsmE. | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | 0.510 |
AGE27602.1 | AGE27604.1 | H045_17700 | H045_17710 | DNA-binding transcriptional activator OsmE. | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | 0.510 |
AGE27602.1 | ribA | H045_17700 | H045_17715 | DNA-binding transcriptional activator OsmE. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.510 |
AGE27603.1 | AGE27602.1 | H045_17705 | H045_17700 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | DNA-binding transcriptional activator OsmE. | 0.510 |
AGE27603.1 | AGE27604.1 | H045_17705 | H045_17710 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | 0.800 |
AGE27603.1 | AGE27606.1 | H045_17705 | H045_17720 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | 0.559 |
AGE27603.1 | nusB | H045_17705 | H045_17730 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.454 |
AGE27603.1 | ribA | H045_17705 | H045_17715 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.802 |
AGE27603.1 | ribB | H045_17705 | H045_17740 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.452 |
AGE27603.1 | ribD | H045_17705 | H045_17750 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.505 |
AGE27603.1 | ribH | H045_17705 | H045_17735 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.430 |
AGE27603.1 | thiL | H045_17705 | H045_17725 | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.471 |
AGE27604.1 | AGE27602.1 | H045_17710 | H045_17700 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | DNA-binding transcriptional activator OsmE. | 0.510 |
AGE27604.1 | AGE27603.1 | H045_17710 | H045_17705 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | Hypothetical protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component. | 0.800 |
AGE27604.1 | AGE27606.1 | H045_17710 | H045_17720 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | 0.555 |
AGE27604.1 | nusB | H045_17710 | H045_17730 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.454 |
AGE27604.1 | ribA | H045_17710 | H045_17715 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.800 |
AGE27604.1 | ribB | H045_17710 | H045_17740 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.461 |
AGE27604.1 | ribD | H045_17710 | H045_17750 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.432 |
AGE27604.1 | ribH | H045_17710 | H045_17735 | Hypothetical protein; COG3425 3-hydroxy-3-methylglutaryl CoA synthase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.430 |