node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE25903.1 | AGE27750.1 | H045_09165 | H045_18440 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.665 |
AGE25903.1 | AGE27988.1 | H045_09165 | H045_19630 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.584 |
AGE25903.1 | AGE28871.1 | H045_09165 | H045_24065 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Beta alanine--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.584 |
AGE25903.1 | bioA | H045_09165 | H045_19065 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.584 |
AGE25903.1 | bioB | H045_09165 | H045_18450 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.540 |
AGE25903.1 | bioD | H045_09165 | H045_18430 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.622 |
AGE25903.1 | bioF | H045_09165 | H045_18445 | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.688 |
AGE27747.1 | AGE27750.1 | H045_18425 | H045_18440 | Hypothetical protein. | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.577 |
AGE27747.1 | bioB | H045_18425 | H045_18450 | Hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.420 |
AGE27747.1 | bioC | H045_18425 | H045_18435 | Hypothetical protein. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.574 |
AGE27747.1 | bioD | H045_18425 | H045_18430 | Hypothetical protein. | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.577 |
AGE27747.1 | bioF | H045_18425 | H045_18445 | Hypothetical protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.577 |
AGE27750.1 | AGE25903.1 | H045_18440 | H045_09165 | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.665 |
AGE27750.1 | AGE27747.1 | H045_18440 | H045_18425 | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein. | 0.577 |
AGE27750.1 | bioB | H045_18440 | H045_18450 | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.717 |
AGE27750.1 | bioC | H045_18440 | H045_18435 | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.993 |
AGE27750.1 | bioD | H045_18440 | H045_18430 | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.924 |
AGE27750.1 | bioF | H045_18440 | H045_18445 | Carboxylesterase BioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.992 |
AGE27988.1 | AGE25903.1 | H045_19630 | H045_09165 | Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.584 |
AGE27988.1 | bioB | H045_19630 | H045_18450 | Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.697 |