STRINGSTRING
AGE27782.1 AGE27782.1 AGE27781.1 AGE27781.1 AGE27783.1 AGE27783.1 AGE27784.1 AGE27784.1 gcvP gcvP glyA-2 glyA-2 glyA glyA AGE27787.1 AGE27787.1 AGE27023.1 AGE27023.1 AGE27788.1 AGE27788.1 gcvH-2 gcvH-2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
AGE27782.1Sarcosine oxidase subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. (1005 aa)    
Predicted Functional Partners:
AGE27781.1
COG4583 Sarcosine oxidase gamma subunit.
 
 0.999
AGE27783.1
COG4311 Sarcosine oxidase delta subunit.
 0.999
AGE27784.1
Sarcosine oxidase subunit beta; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 0.999
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.996
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.990
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.970
AGE27787.1
Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
   
 0.942
AGE27023.1
COG2008 Threonine aldolase.
   
 0.918
AGE27788.1
Hybrid-cluster NAD(P)-dependent oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
 
 
 0.918
gcvH-2
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.863
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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