STRINGSTRING
AGE27784.1 AGE27784.1 AGE27782.1 AGE27782.1 AGE27783.1 AGE27783.1 AGE27781.1 AGE27781.1 glyA-2 glyA-2 AGE27787.1 AGE27787.1 gcvP gcvP glyA glyA AGE27023.1 AGE27023.1 AGE27793.1 AGE27793.1 AGE27789.1 AGE27789.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
AGE27784.1Sarcosine oxidase subunit beta; COG0665 Glycine/D-amino acid oxidases (deaminating). (416 aa)    
Predicted Functional Partners:
AGE27782.1
Sarcosine oxidase subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
 
 0.999
AGE27783.1
COG4311 Sarcosine oxidase delta subunit.
 
 0.998
AGE27781.1
COG4583 Sarcosine oxidase gamma subunit.
 
 0.997
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.973
AGE27787.1
Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
    
 0.937
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.914
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.913
AGE27023.1
COG2008 Threonine aldolase.
     
 0.900
AGE27793.1
Oxidoreductase, FAD/FMN dependent; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
 
 
 0.866
AGE27789.1
Putative iron/sulfur-binding protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
 
    0.851
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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