node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24222.1 | AGE27910.1 | H045_00730 | H045_19240 | Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family. | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.757 |
AGE24296.1 | AGE27910.1 | H045_01100 | H045_19240 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.764 |
AGE24296.1 | AGE27917.1 | H045_01100 | H045_19275 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | HemN family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.516 |
AGE24296.1 | rlmN | H045_01100 | H045_16170 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.444 |
AGE27909.1 | AGE27910.1 | H045_19235 | H045_19240 | Twitching mobility protein; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.611 |
AGE27909.1 | AGE27912.1 | H045_19235 | H045_19250 | Twitching mobility protein; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | YGGT family protein; COG0762 Predicted integral membrane protein. | 0.520 |
AGE27909.1 | proC | H045_19235 | H045_19245 | Twitching mobility protein; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.563 |
AGE27910.1 | AGE24222.1 | H045_19240 | H045_00730 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.757 |
AGE27910.1 | AGE24296.1 | H045_19240 | H045_01100 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.764 |
AGE27910.1 | AGE27909.1 | H045_19240 | H045_19235 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Twitching mobility protein; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.611 |
AGE27910.1 | AGE27912.1 | H045_19240 | H045_19250 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | YGGT family protein; COG0762 Predicted integral membrane protein. | 0.848 |
AGE27910.1 | AGE27917.1 | H045_19240 | H045_19275 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | HemN family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.648 |
AGE27910.1 | murF | H045_19240 | H045_01445 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.577 |
AGE27910.1 | pdxY | H045_19240 | H045_20770 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.664 |
AGE27910.1 | proC | H045_19240 | H045_19245 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.853 |
AGE27910.1 | rdgB | H045_19240 | H045_19270 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.565 |
AGE27910.1 | rlmN | H045_19240 | H045_16170 | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.547 |
AGE27912.1 | AGE27909.1 | H045_19250 | H045_19235 | YGGT family protein; COG0762 Predicted integral membrane protein. | Twitching mobility protein; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.520 |
AGE27912.1 | AGE27910.1 | H045_19250 | H045_19240 | YGGT family protein; COG0762 Predicted integral membrane protein. | Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.848 |
AGE27912.1 | AGE27917.1 | H045_19250 | H045_19275 | YGGT family protein; COG0762 Predicted integral membrane protein. | HemN family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.482 |