STRINGSTRING
thiG thiG AGE27921.1 AGE27921.1 thiO thiO thiE thiE thiC thiC AGE26868.1 AGE26868.1 thiI thiI dxs dxs AGE27539.1 AGE27539.1 AGE24181.1 AGE24181.1 AGE27172.1 AGE27172.1
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thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (264 aa)    
Predicted Functional Partners:
AGE27921.1
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
 
 
 0.998
thiO
Putative oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 0.995
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.977
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.970
AGE26868.1
Putative sulfurylase; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
 
  
 0.948
thiI
tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 
 0.946
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.935
AGE27539.1
Bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
  
 0.926
AGE24181.1
Molybdopterin biosynthesis protein MoeB; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
 
  
 0.892
AGE27172.1
Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
 
  
 0.852
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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