node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24502.1 | AGE25950.1 | H045_02130 | H045_09415 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Cystathionine beta-synthase; COG0031 Cysteine synthase. | 0.908 |
AGE24502.1 | AGE27237.1 | H045_02130 | H045_15860 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | COG0460 Homoserine dehydrogenase. | 0.882 |
AGE24502.1 | ilvA | H045_02130 | H045_19505 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.927 |
AGE24502.1 | trpA | H045_02130 | H045_21290 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.904 |
AGE24502.1 | trpB | H045_02130 | H045_21295 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
AGE25619.1 | AGE27237.1 | H045_07745 | H045_15860 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG0460 Homoserine dehydrogenase. | 0.957 |
AGE25619.1 | AGE27397.1 | H045_07745 | H045_16670 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | Acetolactate synthase 3 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 0.920 |
AGE25619.1 | ilvA | H045_07745 | H045_19505 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.938 |
AGE25619.1 | ilvH | H045_07745 | H045_16665 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.985 |
AGE25619.1 | leuB | H045_07745 | H045_12200 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.938 |
AGE25950.1 | AGE24502.1 | H045_09415 | H045_02130 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.908 |
AGE25950.1 | AGE27237.1 | H045_09415 | H045_15860 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | COG0460 Homoserine dehydrogenase. | 0.883 |
AGE25950.1 | ilvA | H045_09415 | H045_19505 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.936 |
AGE25950.1 | trpA | H045_09415 | H045_21290 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.919 |
AGE25950.1 | trpB | H045_09415 | H045_21295 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.908 |
AGE27236.1 | AGE27237.1 | H045_15855 | H045_15860 | COG0498 Threonine synthase. | COG0460 Homoserine dehydrogenase. | 0.988 |
AGE27236.1 | ilvA | H045_15855 | H045_19505 | COG0498 Threonine synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.966 |
AGE27236.1 | ilvH | H045_15855 | H045_16665 | COG0498 Threonine synthase. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.560 |
AGE27236.1 | leuB | H045_15855 | H045_12200 | COG0498 Threonine synthase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.533 |
AGE27236.1 | trpB | H045_15855 | H045_21295 | COG0498 Threonine synthase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.402 |