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cyaA cyaA cpdA cpdA AGE26191.1 AGE26191.1 pyk pyk AGE26753.1 AGE26753.1 AGE28118.1 AGE28118.1 mazG mazG ndk ndk folE folE AGE26975.1 AGE26975.1 folE-2 folE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
cyaACOG3072 Adenylate cyclase. (946 aa)    
Predicted Functional Partners:
cpdA
Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.963
AGE26191.1
Putative cAMP phosphodiesterase; COG1409 Predicted phosphohydrolases.
     
 0.913
pyk
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.903
AGE26753.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.901
AGE28118.1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.901
mazG
Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase.
     
 0.900
ndk
Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
folE
COG0302 GTP cyclohydrolase I.
     
  0.800
AGE26975.1
Molybdenum cofactor synthesis domain-containing protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
folE-2
COG0302 GTP cyclohydrolase I.
     
  0.800
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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