node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE24204.1 | glmM | H045_00640 | H045_16845 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.405 |
AGE24204.1 | glmS | H045_00640 | H045_20930 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.448 |
AGE24204.1 | glmU | H045_00640 | H045_20940 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.770 |
AGE24204.1 | prs | H045_00640 | H045_00490 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.563 |
AGE25011.1 | AGE25012.1 | H045_04675 | H045_04680 | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.990 |
AGE25011.1 | AGE25023.1 | H045_04675 | H045_04735 | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | Nucleotide sugar epimerase/dehydratase WbpM; COG1086 Predicted nucleoside-diphosphate sugar epimerases. | 0.965 |
AGE25011.1 | glmU | H045_04675 | H045_20940 | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.922 |
AGE25011.1 | lpxA | H045_04675 | H045_03220 | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.831 |
AGE25011.1 | murA | H045_04675 | H045_01240 | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.907 |
AGE25012.1 | AGE25011.1 | H045_04680 | H045_04675 | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | 0.990 |
AGE25012.1 | AGE25023.1 | H045_04680 | H045_04735 | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | Nucleotide sugar epimerase/dehydratase WbpM; COG1086 Predicted nucleoside-diphosphate sugar epimerases. | 0.939 |
AGE25012.1 | glmU | H045_04680 | H045_20940 | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.910 |
AGE25012.1 | lpxA | H045_04680 | H045_03220 | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.827 |
AGE25012.1 | murA | H045_04680 | H045_01240 | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.906 |
AGE25023.1 | AGE25011.1 | H045_04735 | H045_04675 | Nucleotide sugar epimerase/dehydratase WbpM; COG1086 Predicted nucleoside-diphosphate sugar epimerases. | UDP-glucose/GDP-mannose dehydrogenase-like protein; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | 0.965 |
AGE25023.1 | AGE25012.1 | H045_04735 | H045_04680 | Nucleotide sugar epimerase/dehydratase WbpM; COG1086 Predicted nucleoside-diphosphate sugar epimerases. | WbpP; COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.939 |
AGE25023.1 | glmU | H045_04735 | H045_20940 | Nucleotide sugar epimerase/dehydratase WbpM; COG1086 Predicted nucleoside-diphosphate sugar epimerases. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.925 |
AGE27713.1 | glmU | H045_18255 | H045_20940 | COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.919 |
glmM | AGE24204.1 | H045_16845 | H045_00640 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.405 |
glmM | glmS | H045_16845 | H045_20930 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.966 |