node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE28301.1 | AGE28304.1 | H045_21195 | H045_21210 | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | COG1652 Uncharacterized protein containing LysM domain. | 0.477 |
AGE28301.1 | dprA | H045_21195 | H045_21215 | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Hypothetical protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.458 |
AGE28301.1 | ksgA | H045_21195 | H045_18275 | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.605 |
AGE28301.1 | tsaC | H045_21195 | H045_21220 | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.472 |
AGE28304.1 | AGE28301.1 | H045_21210 | H045_21195 | COG1652 Uncharacterized protein containing LysM domain. | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.477 |
AGE28304.1 | dprA | H045_21210 | H045_21215 | COG1652 Uncharacterized protein containing LysM domain. | Hypothetical protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.640 |
AGE28304.1 | tsaC | H045_21210 | H045_21220 | COG1652 Uncharacterized protein containing LysM domain. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.509 |
AGE28743.1 | metG | H045_23425 | H045_02695 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.512 |
AGE28743.1 | tsaB | H045_23425 | H045_03030 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Putative glycoprotease family protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. | 0.958 |
AGE28743.1 | tsaC | H045_23425 | H045_21220 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.675 |
AGE28743.1 | tsaD | H045_23425 | H045_18330 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.901 |
aroE | metG | H045_21235 | H045_02695 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.527 |
aroE | tsaC | H045_21235 | H045_21220 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.429 |
dprA | AGE28301.1 | H045_21215 | H045_21195 | Hypothetical protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.458 |
dprA | AGE28304.1 | H045_21215 | H045_21210 | Hypothetical protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | COG1652 Uncharacterized protein containing LysM domain. | 0.640 |
dprA | tsaC | H045_21215 | H045_21220 | Hypothetical protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.666 |
glmS | metG | H045_20930 | H045_02695 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.641 |
glmS | tsaC | H045_20930 | H045_21220 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.425 |
ksgA | AGE28301.1 | H045_18275 | H045_21195 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.605 |
ksgA | metG | H045_18275 | H045_02695 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.652 |