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msrA msrA msrB msrB polA polA AGE26639.1 AGE26639.1 AGE28689.1 AGE28689.1 dsbD dsbD AGE25110.1 AGE25110.1 AGE26287.1 AGE26287.1 AGE27976.1 AGE27976.1 AGE26528.1 AGE26528.1 cysC cysC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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msrAMethionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (215 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.989
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.815
AGE26639.1
Putative thiol:disulfide interchange protein; COG0682 Prolipoprotein diacylglyceryltransferase.
   
 0.704
AGE28689.1
Sensory box-containing diguanylate cyclase; COG2199 FOG: GGDEF domain.
       0.652
dsbD
Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
 
 0.627
AGE25110.1
Cytochrome C biogenesis, thiol:disulfide interchange protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.582
AGE26287.1
Putative thioredoxin-like protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.582
AGE27976.1
Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.578
AGE26528.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
     
 0.537
cysC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
  
 0.530
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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