STRINGSTRING
glnE glnE glnD glnD waaC waaC glnA glnA AGE28076.1 AGE28076.1 gltB gltB hrpA hrpA argA argA waaF waaF AGE28695.1 AGE28695.1 AGE28696.1 AGE28696.1
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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glnEBifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] (979 aa)    
Predicted Functional Partners:
glnD
PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.813
waaC
Lipopolysaccharide heptosyltransferase I; COG0859 ADP-heptose:LPS heptosyltransferase.
      0.682
glnA
COG0174 Glutamine synthetase.
 
  
 0.633
AGE28076.1
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 
 
 
 0.566
gltB
COG0067 Glutamate synthase domain 1.
     
 0.561
hrpA
COG1643 HrpA-like helicases.
  
     0.538
argA
N-acetylglutamate synthase; COG0548 Acetylglutamate kinase.
     
 0.511
waaF
Lipopolysaccharide heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase.
       0.510
AGE28695.1
Lipopolysaccharide core biosynthesis protein; COG0438 Glycosyltransferase.
       0.510
AGE28696.1
Lipopolysaccharide core heptose(I) kinase RfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.
       0.510
Your Current Organism:
Pseudomonas poae
NCBI taxonomy Id: 1282356
Other names: P. poae RE*1-1-14, Pseudomonas poae RE*1-1-14
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