node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGE26054.1 | nadE | H045_09935 | H045_23575 | Isochorismatase family protein; COG1335 Amidases related to nicotinamidase. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.605 |
AGE26054.1 | pncB | H045_09935 | H045_23580 | Isochorismatase family protein; COG1335 Amidases related to nicotinamidase. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.978 |
AGE28381.1 | AGE28382.1 | H045_21595 | H045_21600 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |
AGE28381.1 | AGE28383.1 | H045_21595 | H045_21605 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |
AGE28381.1 | mazG | H045_21595 | H045_13435 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. | 0.902 |
AGE28381.1 | nadD | H045_21595 | H045_17525 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
AGE28381.1 | nadE | H045_21595 | H045_23575 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.913 |
AGE28381.1 | nudC | H045_21595 | H045_09945 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.900 |
AGE28381.1 | ppnK | H045_21595 | H045_09855 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.908 |
AGE28381.1 | sthA | H045_21595 | H045_04355 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.911 |
AGE28382.1 | AGE28381.1 | H045_21600 | H045_21595 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
AGE28382.1 | AGE28383.1 | H045_21600 | H045_21605 | COG3288 NAD/NADP transhydrogenase alpha subunit. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |
AGE28382.1 | mazG | H045_21600 | H045_13435 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Nucleoside triphosphate pyrophosphohydrolase; COG1694 Predicted pyrophosphatase. | 0.900 |
AGE28382.1 | nadD | H045_21600 | H045_17525 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.906 |
AGE28382.1 | nadE | H045_21600 | H045_23575 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.902 |
AGE28382.1 | nudC | H045_21600 | H045_09945 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.900 |
AGE28382.1 | ppnK | H045_21600 | H045_09855 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.919 |
AGE28382.1 | sthA | H045_21600 | H045_04355 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.918 |
AGE28383.1 | AGE28381.1 | H045_21605 | H045_21595 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
AGE28383.1 | AGE28382.1 | H045_21605 | H045_21600 | COG3288 NAD/NADP transhydrogenase alpha subunit. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |