node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGI22108.1 | AGI22110.1 | H681_01130 | H681_01140 | Hypothetical protein. | Cobalamin synthesis protein, P47K; COG0523 Putative GTPases (G3E family). | 0.683 |
AGI22108.1 | dksA | H681_01130 | H681_01135 | Hypothetical protein. | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.599 |
AGI22108.1 | folE2 | H681_01130 | H681_01125 | Hypothetical protein. | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.674 |
AGI22110.1 | AGI22108.1 | H681_01140 | H681_01130 | Cobalamin synthesis protein, P47K; COG0523 Putative GTPases (G3E family). | Hypothetical protein. | 0.683 |
AGI22110.1 | dksA | H681_01140 | H681_01135 | Cobalamin synthesis protein, P47K; COG0523 Putative GTPases (G3E family). | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.901 |
AGI22110.1 | folE2 | H681_01140 | H681_01125 | Cobalamin synthesis protein, P47K; COG0523 Putative GTPases (G3E family). | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.815 |
dksA | AGI22108.1 | H681_01135 | H681_01130 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Hypothetical protein. | 0.599 |
dksA | AGI22110.1 | H681_01135 | H681_01140 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Cobalamin synthesis protein, P47K; COG0523 Putative GTPases (G3E family). | 0.901 |
dksA | folE2 | H681_01135 | H681_01125 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.721 |
dksA | greA | H681_01135 | H681_21115 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | 0.533 |
dksA | hfq | H681_01135 | H681_22145 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.667 |
dksA | rpoB | H681_01135 | H681_02740 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.622 |
dksA | rpoC | H681_01135 | H681_02745 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.732 |
dksA | rpoD | H681_01135 | H681_02415 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.568 |
dksA | rpoZ | H681_01135 | H681_24240 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.845 |
dksA | tolQ | H681_01135 | H681_17795 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.529 |
folE2 | AGI22108.1 | H681_01125 | H681_01130 | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | Hypothetical protein. | 0.674 |
folE2 | AGI22110.1 | H681_01125 | H681_01140 | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | Cobalamin synthesis protein, P47K; COG0523 Putative GTPases (G3E family). | 0.815 |
folE2 | dksA | H681_01125 | H681_01135 | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.721 |
greA | dksA | H681_21115 | H681_01135 | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.533 |