node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGI22124.1 | AGI22245.1 | H681_01210 | H681_01815 | Hypothetical protein; COG0517 FOG: CBS domain. | Cystathionine beta-synthase; COG0031 Cysteine synthase. | 0.439 |
AGI22124.1 | AGI22517.1 | H681_01210 | H681_03175 | Hypothetical protein; COG0517 FOG: CBS domain. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.550 |
AGI22124.1 | AGI24072.1 | H681_01210 | H681_11010 | Hypothetical protein; COG0517 FOG: CBS domain. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.410 |
AGI22124.1 | birA | H681_01210 | H681_02690 | Hypothetical protein; COG0517 FOG: CBS domain. | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.465 |
AGI22124.1 | gltB | H681_01210 | H681_22595 | Hypothetical protein; COG0517 FOG: CBS domain. | COG0067 Glutamate synthase domain 1. | 0.509 |
AGI22124.1 | guaA | H681_01210 | H681_18770 | Hypothetical protein; COG0517 FOG: CBS domain. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.761 |
AGI22124.1 | htpG | H681_01210 | H681_13910 | Hypothetical protein; COG0517 FOG: CBS domain. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.562 |
AGI22124.1 | prs | H681_01210 | H681_20660 | Hypothetical protein; COG0517 FOG: CBS domain. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.443 |
AGI22124.1 | purL | H681_01210 | H681_18750 | Hypothetical protein; COG0517 FOG: CBS domain. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.673 |
AGI22124.1 | ribB | H681_01210 | H681_03185 | Hypothetical protein; COG0517 FOG: CBS domain. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.578 |
AGI22245.1 | AGI22124.1 | H681_01815 | H681_01210 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | Hypothetical protein; COG0517 FOG: CBS domain. | 0.439 |
AGI22245.1 | AGI22517.1 | H681_01815 | H681_03175 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.412 |
AGI22245.1 | gltB | H681_01815 | H681_22595 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | COG0067 Glutamate synthase domain 1. | 0.579 |
AGI22245.1 | guaA | H681_01815 | H681_18770 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.571 |
AGI22245.1 | purL | H681_01815 | H681_18750 | Cystathionine beta-synthase; COG0031 Cysteine synthase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.484 |
AGI22517.1 | AGI22124.1 | H681_03175 | H681_01210 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; COG0517 FOG: CBS domain. | 0.550 |
AGI22517.1 | AGI22245.1 | H681_03175 | H681_01815 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Cystathionine beta-synthase; COG0031 Cysteine synthase. | 0.412 |
AGI22517.1 | AGI24072.1 | H681_03175 | H681_11010 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.405 |
AGI22517.1 | birA | H681_03175 | H681_02690 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.646 |
AGI22517.1 | gltB | H681_03175 | H681_22595 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0067 Glutamate synthase domain 1. | 0.476 |