node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGI22417.1 | AGI22418.1 | H681_02675 | H681_02680 | COG0739 Membrane proteins related to metalloendopeptidases. | Hypothetical protein. | 0.561 |
AGI22417.1 | AGI26299.1 | H681_02675 | H681_22160 | COG0739 Membrane proteins related to metalloendopeptidases. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.702 |
AGI22417.1 | anmK | H681_02675 | H681_02670 | COG0739 Membrane proteins related to metalloendopeptidases. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.897 |
AGI22417.1 | mltG | H681_02675 | H681_16025 | COG0739 Membrane proteins related to metalloendopeptidases. | Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.495 |
AGI22417.1 | tyrS | H681_02675 | H681_02685 | COG0739 Membrane proteins related to metalloendopeptidases. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.500 |
AGI22418.1 | AGI22417.1 | H681_02680 | H681_02675 | Hypothetical protein. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.561 |
AGI22418.1 | anmK | H681_02680 | H681_02670 | Hypothetical protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.561 |
AGI22418.1 | tyrS | H681_02680 | H681_02685 | Hypothetical protein. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.471 |
AGI22517.1 | anmK | H681_03175 | H681_02670 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.533 |
AGI22517.1 | mltG | H681_03175 | H681_16025 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.539 |
AGI22875.1 | AGI26299.1 | H681_04975 | H681_22160 | N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.437 |
AGI22875.1 | anmK | H681_04975 | H681_02670 | N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.516 |
AGI26299.1 | AGI22417.1 | H681_22160 | H681_02675 | COG0860 N-acetylmuramoyl-L-alanine amidase. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.702 |
AGI26299.1 | AGI22875.1 | H681_22160 | H681_04975 | COG0860 N-acetylmuramoyl-L-alanine amidase. | N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression. | 0.437 |
AGI26299.1 | anmK | H681_22160 | H681_02670 | COG0860 N-acetylmuramoyl-L-alanine amidase. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.459 |
AGI26299.1 | mltG | H681_22160 | H681_16025 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.562 |
AGI26299.1 | nagZ | H681_22160 | H681_16210 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.452 |
anmK | AGI22417.1 | H681_02670 | H681_02675 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.897 |
anmK | AGI22418.1 | H681_02670 | H681_02680 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein. | 0.561 |
anmK | AGI22517.1 | H681_02670 | H681_03175 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.533 |