node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGI22815.1 | coaD | H681_04675 | H681_01630 | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.723 |
AGI22815.1 | coaE | H681_04675 | H681_04920 | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.642 |
AGI22815.1 | guaB | H681_04675 | H681_18775 | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.642 |
AGI22815.1 | polA | H681_04675 | H681_01035 | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.512 |
AGI22865.1 | AGI22866.1 | H681_04925 | H681_04930 | Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Pilin biogenesis protein; COG1459 Type II secretory pathway, component PulF. | 0.973 |
AGI22865.1 | AGI22867.1 | H681_04925 | H681_04935 | Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | 0.972 |
AGI22865.1 | coaE | H681_04925 | H681_04920 | Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.772 |
AGI22865.1 | yacG | H681_04925 | H681_04915 | Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.633 |
AGI22866.1 | AGI22865.1 | H681_04930 | H681_04925 | Pilin biogenesis protein; COG1459 Type II secretory pathway, component PulF. | Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.973 |
AGI22866.1 | AGI22867.1 | H681_04930 | H681_04935 | Pilin biogenesis protein; COG1459 Type II secretory pathway, component PulF. | Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | 0.986 |
AGI22866.1 | coaE | H681_04930 | H681_04920 | Pilin biogenesis protein; COG1459 Type II secretory pathway, component PulF. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.633 |
AGI22866.1 | yacG | H681_04930 | H681_04915 | Pilin biogenesis protein; COG1459 Type II secretory pathway, component PulF. | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.633 |
AGI22867.1 | AGI22865.1 | H681_04935 | H681_04925 | Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.972 |
AGI22867.1 | AGI22866.1 | H681_04935 | H681_04930 | Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Pilin biogenesis protein; COG1459 Type II secretory pathway, component PulF. | 0.986 |
AGI22867.1 | coaE | H681_04935 | H681_04920 | Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.621 |
AGI22867.1 | yacG | H681_04935 | H681_04915 | Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.611 |
coaD | AGI22815.1 | H681_01630 | H681_04675 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. | 0.723 |
coaD | coaE | H681_01630 | H681_04920 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.950 |
coaD | guaB | H681_01630 | H681_18775 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.452 |
coaE | AGI22815.1 | H681_04920 | H681_04675 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. | 0.642 |