node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGI23220.1 | AGI23222.1 | H681_06720 | H681_06730 | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.713 |
AGI23220.1 | AGI23395.1 | H681_06720 | H681_07595 | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | Hypothetical protein; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.509 |
AGI23220.1 | era | H681_06720 | H681_06745 | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.489 |
AGI23220.1 | lepA | H681_06720 | H681_06725 | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.613 |
AGI23220.1 | rnc | H681_06720 | H681_06740 | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.400 |
AGI23222.1 | AGI23220.1 | H681_06730 | H681_06720 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | 0.713 |
AGI23222.1 | AGI23395.1 | H681_06730 | H681_07595 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Hypothetical protein; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.682 |
AGI23222.1 | era | H681_06730 | H681_06745 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.658 |
AGI23222.1 | ftsI | H681_06730 | H681_04420 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.657 |
AGI23222.1 | lepA | H681_06730 | H681_06725 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.943 |
AGI23222.1 | minE | H681_06730 | H681_17445 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.674 |
AGI23222.1 | parC | H681_06730 | H681_22260 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.722 |
AGI23222.1 | rnc | H681_06730 | H681_06740 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.780 |
AGI23222.1 | secY | H681_06730 | H681_02875 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.795 |
AGI23222.1 | yidC | H681_06730 | H681_25340 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.787 |
AGI23395.1 | AGI23220.1 | H681_07595 | H681_06720 | Hypothetical protein; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | 0.509 |
AGI23395.1 | AGI23222.1 | H681_07595 | H681_06730 | Hypothetical protein; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.682 |
era | AGI23220.1 | H681_06745 | H681_06720 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. | 0.489 |
era | AGI23222.1 | H681_06745 | H681_06730 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.658 |
era | lepA | H681_06745 | H681_06725 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.819 |