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rnc rnc rpsO rpsO era era rpmA rpmA rpsI rpsI rplM rplM rpsB rpsB rpsP rpsP rpsF rpsF rpsL rpsL rpmF rpmF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (229 aa)    
Predicted Functional Partners:
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
 
 
 0.927
era
GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
  
 0.923
rpmA
COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.920
rpsI
COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.918
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.917
rpsB
COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.916
rpsP
COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.902
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.902
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.900
rpmF
COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.899
Your Current Organism:
Pseudomonas sp. ATCC 13867
NCBI taxonomy Id: 1294143
Other names: P. sp. ATCC 13867, Pseudomonas denitrificans ATCC 13867
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