STRINGSTRING
cysM cysM AGI25656.1 AGI25656.1 cysC cysC rumA rumA metZ metZ AGI25594.1 AGI25594.1 AGI22246.1 AGI22246.1 AGI23458.1 AGI23458.1 AGI23455.1 AGI23455.1 cysS cysS AGI23454.1 AGI23454.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cysMCOG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (299 aa)    
Predicted Functional Partners:
AGI25656.1
COG1045 Serine acetyltransferase.
 
 0.983
cysC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.878
rumA
23S rRNA m(5)U1939 methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
  
    0.824
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
 0.723
AGI25594.1
COG0460 Homoserine dehydrogenase.
 
 
 0.686
AGI22246.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.672
AGI23458.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
   
 0.653
AGI23455.1
COG0642 Signal transduction histidine kinase.
       0.622
cysS
COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.613
AGI23454.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
     
 0.606
Your Current Organism:
Pseudomonas sp. ATCC 13867
NCBI taxonomy Id: 1294143
Other names: P. sp. ATCC 13867, Pseudomonas denitrificans ATCC 13867
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