STRINGSTRING
AGI25111.1 AGI25111.1 nagZ nagZ AGI25109.1 AGI25109.1 AGI25112.1 AGI25112.1 AGI24615.1 AGI24615.1 AGI26395.1 AGI26395.1 AGI22088.1 AGI22088.1 lexA lexA AGI25114.1 AGI25114.1 AGI23017.1 AGI23017.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AGI25111.1COG1376 Uncharacterized protein conserved in bacteria. (174 aa)    
Predicted Functional Partners:
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
     0.828
AGI25109.1
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
 
     0.821
AGI25112.1
COG1309 Transcriptional regulator.
       0.677
AGI24615.1
COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
      0.615
AGI26395.1
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
     
 0.523
AGI22088.1
Hypothetical protein.
  
     0.480
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.455
AGI25114.1
Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
       0.444
AGI23017.1
Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
 
     0.411
Your Current Organism:
Pseudomonas sp. ATCC 13867
NCBI taxonomy Id: 1294143
Other names: P. sp. ATCC 13867, Pseudomonas denitrificans ATCC 13867
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