STRINGSTRING
AGI25112.1 AGI25112.1 AGI25111.1 AGI25111.1 nagZ nagZ AGI25109.1 AGI25109.1 lexA lexA AGI25114.1 AGI25114.1 AGI23374.1 AGI23374.1 AGI25922.1 AGI25922.1 AGI24903.1 AGI24903.1 AGI23397.1 AGI23397.1 AGI24364.1 AGI24364.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AGI25112.1COG1309 Transcriptional regulator. (233 aa)    
Predicted Functional Partners:
AGI25111.1
COG1376 Uncharacterized protein conserved in bacteria.
       0.677
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
     
 0.671
AGI25109.1
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
     
 0.667
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.552
AGI25114.1
Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
       0.503
AGI23374.1
Hypothetical protein.
  
     0.459
AGI25922.1
Transcriptional regulator MvaT, P16 subunit.
  
   
 0.446
AGI24903.1
COG3198 Uncharacterized protein conserved in bacteria.
  
    0.422
AGI23397.1
COG2825 Outer membrane protein.
  
    0.417
AGI24364.1
Transcriptional regulator MvaV; COG4992 Ornithine/acetylornithine aminotransferase.
  
     0.407
Your Current Organism:
Pseudomonas sp. ATCC 13867
NCBI taxonomy Id: 1294143
Other names: P. sp. ATCC 13867, Pseudomonas denitrificans ATCC 13867
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