STRINGSTRING
AGI25367.1 AGI25367.1 AGI25365.1 AGI25365.1 AGI25364.1 AGI25364.1 AGI25366.1 AGI25366.1 AGI25363.1 AGI25363.1 AGI25362.1 AGI25362.1 hisZ hisZ hisF hisF hisH hisH hisI hisI hisA hisA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
AGI25367.1Hypothetical protein; COG0560 Phosphoserine phosphatase. (217 aa)    
Predicted Functional Partners:
AGI25365.1
ABC transporter permease; COG1177 ABC-type spermidine/putrescine transport system, permease component II.
 
    0.868
AGI25364.1
Binding-protein-dependent transport system inner membrane protein; COG4132 ABC-type uncharacterized transport system, permease component.
 
    0.844
AGI25366.1
ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.
 
    0.832
AGI25363.1
COG1524 Uncharacterized proteins of the AP superfamily.
 
     0.795
AGI25362.1
ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.
 
     0.668
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
 
    0.595
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.567
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.534
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.508
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.
  
  
 0.496
Your Current Organism:
Pseudomonas sp. ATCC 13867
NCBI taxonomy Id: 1294143
Other names: P. sp. ATCC 13867, Pseudomonas denitrificans ATCC 13867
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