STRINGSTRING
ttcA ttcA AGI25489.1 AGI25489.1 AGI25491.1 AGI25491.1 AGI25488.1 AGI25488.1 AGI22226.1 AGI22226.1 metG metG AGI25487.1 AGI25487.1 AGI26001.1 AGI26001.1 mfd mfd pheT pheT guaA guaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttcAtRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (275 aa)    
Predicted Functional Partners:
AGI25489.1
Hypothetical protein; COG2818 3-methyladenine DNA glycosylase.
  
  
 0.800
AGI25491.1
Hypothetical protein; COG2214 DnaJ-class molecular chaperone.
  
  
 0.676
AGI25488.1
COG0846 NAD-dependent protein deacetylases, SIR2 family.
       0.671
AGI22226.1
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
  
 
 0.636
metG
methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   
 0.612
AGI25487.1
Putative lipoprotein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
  
    0.533
AGI26001.1
COG0193 Peptidyl-tRNA hydrolase.
  
  
 0.533
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.513
pheT
phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.505
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.492
Your Current Organism:
Pseudomonas sp. ATCC 13867
NCBI taxonomy Id: 1294143
Other names: P. sp. ATCC 13867, Pseudomonas denitrificans ATCC 13867
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.