node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | purC | H681_21130 | H681_17705 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.630 |
carA | purD | H681_21130 | H681_21730 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.815 |
carA | purE | H681_21130 | H681_24460 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.838 |
carA | purF | H681_21130 | H681_16650 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.974 |
carA | purH | H681_21130 | H681_21725 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.783 |
carA | purK | H681_21130 | H681_24455 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.683 |
carA | purL | H681_21130 | H681_18750 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.967 |
carA | purM | H681_21130 | H681_17930 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.812 |
carA | purN | H681_21130 | H681_17935 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.544 |
purC | carA | H681_17705 | H681_21130 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.630 |
purC | purD | H681_17705 | H681_21730 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.984 |
purC | purE | H681_17705 | H681_24460 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | H681_17705 | H681_16650 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.966 |
purC | purH | H681_17705 | H681_21725 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.981 |
purC | purK | H681_17705 | H681_24455 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.988 |
purC | purL | H681_17705 | H681_18750 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
purC | purM | H681_17705 | H681_17930 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.983 |
purC | purN | H681_17705 | H681_17935 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.977 |
purC | purT | H681_17705 | H681_18710 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.688 |
purD | carA | H681_21730 | H681_21130 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.815 |