node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carB | purC | MDS_3925 | MDS_3190 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.522 |
carB | purD | MDS_3925 | MDS_0792 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.748 |
carB | purE | MDS_3925 | MDS_0116 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.919 |
carB | purF | MDS_3925 | MDS_2007 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.991 |
carB | purH | MDS_3925 | MDS_0793 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.677 |
carB | purK | MDS_3925 | MDS_0115 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.470 |
carB | purL | MDS_3925 | MDS_3738 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.670 |
carB | purM | MDS_3925 | MDS_3274 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylaminoimidazole synthetase. | 0.732 |
carB | purN | MDS_3925 | MDS_3275 | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.553 |
purC | carB | MDS_3190 | MDS_3925 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.522 |
purC | purD | MDS_3190 | MDS_0792 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.993 |
purC | purE | MDS_3190 | MDS_0116 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.991 |
purC | purF | MDS_3190 | MDS_2007 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.932 |
purC | purH | MDS_3190 | MDS_0793 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.932 |
purC | purK | MDS_3190 | MDS_0115 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.890 |
purC | purL | MDS_3190 | MDS_3738 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.994 |
purC | purM | MDS_3190 | MDS_3274 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole synthetase. | 0.906 |
purC | purN | MDS_3190 | MDS_3275 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.921 |
purC | purT | MDS_3190 | MDS_3730 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.825 |
purD | carB | MDS_0792 | MDS_3925 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.748 |