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cobB cobB MDS_1611 MDS_1611 nadD nadD nadE nadE nadK nadK sthA sthA MDS_4761 MDS_4761 MDS_1468 MDS_1468 nudC nudC MDS_4762 MDS_4762 MDS_3125 MDS_3125
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobBSilent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. (235 aa)    
Predicted Functional Partners:
MDS_1611
NAD metabolism ATPase/kinase-like protein.
   
 
  0.951
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.935
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.934
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.928
sthA
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.919
MDS_4761
NAD(P)(+) transhydrogenase.
     
 0.917
MDS_1468
Isochorismatase hydrolase.
  
 0.915
nudC
NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily.
    
 0.910
MDS_4762
NAD/NADP transhydrogenase alpha subunit-like protein.
     
 0.909
MDS_3125
Nucleoside triphosphate pyrophosphohydrolase.
    
  0.901
Your Current Organism:
Pseudomonas mendocina NK01
NCBI taxonomy Id: 1001585
Other names: P. mendocina NK-01, Pseudomonas mendocina NK-01, Pseudomonas mendocina str. NK-01, Pseudomonas mendocina strain NK-01
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