node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MDS_0706 | queC | MDS_0706 | MDS_1315 | N-acetylmuramoyl-L-alanine amidase. | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.470 |
MDS_0706 | queD | MDS_0706 | MDS_2769 | N-acetylmuramoyl-L-alanine amidase. | Putative 6-pyruvoyl tetrahydropterin synthase. | 0.462 |
MDS_0706 | queF | MDS_0706 | MDS_2974 | N-acetylmuramoyl-L-alanine amidase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.467 |
MDS_1840 | queC | MDS_1840 | MDS_1315 | Flagellar protein FlaG protein. | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.536 |
nadA | queC | MDS_1316 | MDS_1315 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.483 |
nadA | queE | MDS_1316 | MDS_1314 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.609 |
queA | queC | MDS_3786 | MDS_1315 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.480 |
queA | queF | MDS_3786 | MDS_2974 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.680 |
queC | MDS_0706 | MDS_1315 | MDS_0706 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | N-acetylmuramoyl-L-alanine amidase. | 0.470 |
queC | MDS_1840 | MDS_1315 | MDS_1840 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Flagellar protein FlaG protein. | 0.536 |
queC | nadA | MDS_1315 | MDS_1316 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.483 |
queC | queA | MDS_1315 | MDS_3786 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.480 |
queC | queD | MDS_1315 | MDS_2769 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative 6-pyruvoyl tetrahydropterin synthase. | 0.913 |
queC | queE | MDS_1315 | MDS_1314 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
queC | queF | MDS_1315 | MDS_2974 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.992 |
queC | tolQ | MDS_1315 | MDS_1308 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | MotA/TolQ/ExbB proton channel; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.450 |
queC | trmJ | MDS_1315 | MDS_3779 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.457 |
queC | ygbF | MDS_1315 | MDS_1313 | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | TPR repeat-containing protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.522 |
queD | MDS_0706 | MDS_2769 | MDS_0706 | Putative 6-pyruvoyl tetrahydropterin synthase. | N-acetylmuramoyl-L-alanine amidase. | 0.462 |
queD | queC | MDS_2769 | MDS_1315 | Putative 6-pyruvoyl tetrahydropterin synthase. | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.913 |