STRINGSTRING
MDS_1642 MDS_1642 nagZ nagZ MDS_1641 MDS_1641 MDS_2365 MDS_2365 MDS_4099 MDS_4099 MDS_0169 MDS_0169 MDS_1639 MDS_1639 lexA lexA MDS_1792 MDS_1792
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
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Experiments
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Textmining
[Homology]
Score
MDS_1642ErfK/YbiS/YcfS/YnhG family protein. (175 aa)    
Predicted Functional Partners:
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
     0.824
MDS_1641
TetR family transcriptional regulator.
       0.660
MDS_2365
GCN5-related N-acetyltransferase.
      0.607
MDS_4099
Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
    
 0.587
MDS_0169
Hypothetical protein.
  
     0.473
MDS_1639
SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
       0.461
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.461
MDS_1792
Amino acid adenylation domain-containing protein.
     
 0.458
Your Current Organism:
Pseudomonas mendocina NK01
NCBI taxonomy Id: 1001585
Other names: P. mendocina NK-01, Pseudomonas mendocina NK-01, Pseudomonas mendocina str. NK-01, Pseudomonas mendocina strain NK-01
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