node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MDS_1639 | MDS_1641 | MDS_1639 | MDS_1641 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | TetR family transcriptional regulator. | 0.535 |
MDS_1639 | MDS_1642 | MDS_1639 | MDS_1642 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | ErfK/YbiS/YcfS/YnhG family protein. | 0.461 |
MDS_1639 | nagZ | MDS_1639 | MDS_1643 | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.453 |
MDS_1641 | MDS_1639 | MDS_1641 | MDS_1639 | TetR family transcriptional regulator. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.535 |
MDS_1641 | MDS_1642 | MDS_1641 | MDS_1642 | TetR family transcriptional regulator. | ErfK/YbiS/YcfS/YnhG family protein. | 0.660 |
MDS_1641 | nagZ | MDS_1641 | MDS_1643 | TetR family transcriptional regulator. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.649 |
MDS_1642 | MDS_1639 | MDS_1642 | MDS_1639 | ErfK/YbiS/YcfS/YnhG family protein. | SOS cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.461 |
MDS_1642 | MDS_1641 | MDS_1642 | MDS_1641 | ErfK/YbiS/YcfS/YnhG family protein. | TetR family transcriptional regulator. | 0.660 |
MDS_1642 | nagZ | MDS_1642 | MDS_1643 | ErfK/YbiS/YcfS/YnhG family protein. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.824 |
MDS_1891 | MDS_3536 | MDS_1891 | MDS_3536 | Hypothetical protein. | Glycoside hydrolase family 3 protein. | 0.641 |
MDS_1891 | nagZ | MDS_1891 | MDS_1643 | Hypothetical protein. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.641 |
MDS_2216 | MDS_3536 | MDS_2216 | MDS_3536 | Lytic transglycosylase, catalytic. | Glycoside hydrolase family 3 protein. | 0.409 |
MDS_2216 | mpl | MDS_2216 | MDS_4130 | Lytic transglycosylase, catalytic. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.424 |
MDS_2216 | nagZ | MDS_2216 | MDS_1643 | Lytic transglycosylase, catalytic. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.490 |
MDS_2793 | MDS_3536 | MDS_2793 | MDS_3536 | Cyclic beta 1-2 glucan synthetase, putative. | Glycoside hydrolase family 3 protein. | 0.456 |
MDS_2793 | nagZ | MDS_2793 | MDS_1643 | Cyclic beta 1-2 glucan synthetase, putative. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.456 |
MDS_3536 | MDS_1891 | MDS_3536 | MDS_1891 | Glycoside hydrolase family 3 protein. | Hypothetical protein. | 0.641 |
MDS_3536 | MDS_2216 | MDS_3536 | MDS_2216 | Glycoside hydrolase family 3 protein. | Lytic transglycosylase, catalytic. | 0.409 |
MDS_3536 | MDS_2793 | MDS_3536 | MDS_2793 | Glycoside hydrolase family 3 protein. | Cyclic beta 1-2 glucan synthetase, putative. | 0.456 |
MDS_3536 | nagZ | MDS_3536 | MDS_1643 | Glycoside hydrolase family 3 protein. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.535 |