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pyk pyk eno eno pgi pgi MDS_0578 MDS_0578 MDS_1904 MDS_1904 MDS_1764 MDS_1764 oadA oadA gmk gmk aceE aceE rpsB rpsB lldD lldD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pykPyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 0.990
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.975
MDS_0578
Malate dehydrogenase.
  
 0.950
MDS_1904
Glycerate 2-kinase.
 
 
 0.946
MDS_1764
Oxaloacetate decarboxylase.
  
 
 0.940
oadA
Pyruvate carboxylase subunit B.
  
 
 0.940
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.938
aceE
Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.932
rpsB
30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.930
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
  
 0.928
Your Current Organism:
Pseudomonas mendocina NK01
NCBI taxonomy Id: 1001585
Other names: P. mendocina NK-01, Pseudomonas mendocina NK-01, Pseudomonas mendocina str. NK-01, Pseudomonas mendocina strain NK-01
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