node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MDS_3101 | MDS_3102 | MDS_3101 | MDS_3102 | Major facilitator transporter. | MarR family transcriptional regulator. | 0.710 |
MDS_3101 | MDS_3104 | MDS_3101 | MDS_3104 | Major facilitator transporter. | Phosphoglycerate mutase. | 0.524 |
MDS_3101 | MDS_3106 | MDS_3101 | MDS_3106 | Major facilitator transporter. | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.524 |
MDS_3101 | MDS_3108 | MDS_3101 | MDS_3108 | Major facilitator transporter. | Threonine-phosphate decarboxylase. | 0.438 |
MDS_3101 | bluB | MDS_3101 | MDS_3110 | Major facilitator transporter. | cob(II)yrinic acid a,c-diamide reductase. | 0.437 |
MDS_3101 | cobB-2 | MDS_3101 | MDS_3111 | Major facilitator transporter. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.431 |
MDS_3101 | cobD | MDS_3101 | MDS_3109 | Major facilitator transporter. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.431 |
MDS_3101 | cobQ | MDS_3101 | MDS_3107 | Major facilitator transporter. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.431 |
MDS_3101 | cobS | MDS_3101 | MDS_3103 | Major facilitator transporter. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.524 |
MDS_3101 | cobT | MDS_3101 | MDS_3105 | Major facilitator transporter. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.524 |
MDS_3102 | MDS_3101 | MDS_3102 | MDS_3101 | MarR family transcriptional regulator. | Major facilitator transporter. | 0.710 |
MDS_3102 | MDS_3104 | MDS_3102 | MDS_3104 | MarR family transcriptional regulator. | Phosphoglycerate mutase. | 0.629 |
MDS_3102 | MDS_3106 | MDS_3102 | MDS_3106 | MarR family transcriptional regulator. | Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.621 |
MDS_3102 | MDS_3108 | MDS_3102 | MDS_3108 | MarR family transcriptional regulator. | Threonine-phosphate decarboxylase. | 0.496 |
MDS_3102 | bluB | MDS_3102 | MDS_3110 | MarR family transcriptional regulator. | cob(II)yrinic acid a,c-diamide reductase. | 0.510 |
MDS_3102 | cobB-2 | MDS_3102 | MDS_3111 | MarR family transcriptional regulator. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.496 |
MDS_3102 | cobD | MDS_3102 | MDS_3109 | MarR family transcriptional regulator. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.496 |
MDS_3102 | cobQ | MDS_3102 | MDS_3107 | MarR family transcriptional regulator. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.496 |
MDS_3102 | cobS | MDS_3102 | MDS_3103 | MarR family transcriptional regulator. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.621 |
MDS_3102 | cobT | MDS_3102 | MDS_3105 | MarR family transcriptional regulator. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.621 |