node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MDS_0862 | MDS_2891 | MDS_0862 | MDS_2891 | Glycine hydroxymethyltransferase. | 5-aminolevulinate synthase. | 0.909 |
MDS_0862 | MDS_4448 | MDS_0862 | MDS_4448 | Glycine hydroxymethyltransferase. | Sarcosine oxidase alpha subunit family protein; Belongs to the GcvT family. | 0.869 |
MDS_0862 | MDS_4450 | MDS_0862 | MDS_4450 | Glycine hydroxymethyltransferase. | Sarcosine oxidase beta subunit family protein. | 0.665 |
MDS_0862 | MDS_4453 | MDS_0862 | MDS_4453 | Glycine hydroxymethyltransferase. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.915 |
MDS_0862 | gcvP | MDS_0862 | MDS_1374 | Glycine hydroxymethyltransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.989 |
MDS_0862 | glyA | MDS_0862 | MDS_0871 | Glycine hydroxymethyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.715 |
MDS_0862 | glyA-2 | MDS_0862 | MDS_1373 | Glycine hydroxymethyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.717 |
MDS_0862 | glyA-3 | MDS_0862 | MDS_1559 | Glycine hydroxymethyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.716 |
MDS_0862 | glyA-4 | MDS_0862 | MDS_4451 | Glycine hydroxymethyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.716 |
MDS_2891 | MDS_0862 | MDS_2891 | MDS_0862 | 5-aminolevulinate synthase. | Glycine hydroxymethyltransferase. | 0.909 |
MDS_2891 | MDS_4448 | MDS_2891 | MDS_4448 | 5-aminolevulinate synthase. | Sarcosine oxidase alpha subunit family protein; Belongs to the GcvT family. | 0.952 |
MDS_2891 | MDS_4450 | MDS_2891 | MDS_4450 | 5-aminolevulinate synthase. | Sarcosine oxidase beta subunit family protein. | 0.905 |
MDS_2891 | MDS_4453 | MDS_2891 | MDS_4453 | 5-aminolevulinate synthase. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.914 |
MDS_2891 | gcvP | MDS_2891 | MDS_1374 | 5-aminolevulinate synthase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.948 |
MDS_2891 | glyA | MDS_2891 | MDS_0871 | 5-aminolevulinate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
MDS_2891 | glyA-2 | MDS_2891 | MDS_1373 | 5-aminolevulinate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
MDS_2891 | glyA-3 | MDS_2891 | MDS_1559 | 5-aminolevulinate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
MDS_2891 | glyA-4 | MDS_2891 | MDS_4451 | 5-aminolevulinate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
MDS_3714 | MDS_4453 | MDS_3714 | MDS_4453 | Threonine synthase. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.932 |
MDS_3714 | gcvP | MDS_3714 | MDS_1374 | Threonine synthase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.515 |