STRINGSTRING
MDS_4483 MDS_4483 metW metW rdgB rdgB metXS metXS MDS_4485 MDS_4485 MDS_4597 MDS_4597 MDS_0305 MDS_0305 MDS_4486 MDS_4486 MDS_2097 MDS_2097 MDS_4480 MDS_4480 MDS_2100 MDS_2100
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDS_4483Hypothetical protein. (138 aa)    
Predicted Functional Partners:
metW
Methionine biosynthesis protein MetW.
     0.941
rdgB
Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.902
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
       0.768
MDS_4485
Hypothetical protein.
       0.628
MDS_4597
Hypothetical protein.
  
     0.612
MDS_0305
Cytochrome c5; It is unreactive with cytochrome c reductase or oxidase but seems to function as an intermediate in nitrate respiration of facultative anaerobic pseudmonads.
  
     0.605
MDS_4486
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.602
MDS_2097
Hypothetical protein.
  
     0.586
MDS_4480
GTPase (dynamin-related)-like protein.
       0.579
MDS_2100
Cbb3-type cytochrome oxidase component.
  
     0.574
Your Current Organism:
Pseudomonas mendocina NK01
NCBI taxonomy Id: 1001585
Other names: P. mendocina NK-01, Pseudomonas mendocina NK-01, Pseudomonas mendocina str. NK-01, Pseudomonas mendocina strain NK-01
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.