STRINGSTRING
MDS_4538 MDS_4538 rdgB rdgB ilvD ilvD MDS_2413 MDS_2413 fghA fghA ahpC ahpC MDS_4636 MDS_4636 gloA-2 gloA-2 MDS_2623 MDS_2623 MDS_4132 MDS_4132 cheB-3 cheB-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDS_4538Phosphodiesterase. (152 aa)    
Predicted Functional Partners:
rdgB
Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.842
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
       0.576
MDS_2413
ATP-dependent DNA ligase.
  
 
 
 0.560
fghA
Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.558
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.445
MDS_4636
1-Cys peroxiredoxin.
   
 
 0.445
gloA-2
Lactoylglutathione lyase.
       0.443
MDS_2623
Protein kinase.
  
  
 0.420
MDS_4132
Protein kinase.
  
  
 0.420
cheB-3
cheB-1; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
     0.404
Your Current Organism:
Pseudomonas mendocina NK01
NCBI taxonomy Id: 1001585
Other names: P. mendocina NK-01, Pseudomonas mendocina NK-01, Pseudomonas mendocina str. NK-01, Pseudomonas mendocina strain NK-01
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.