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ribH ribH ribB ribB MMP1348 MMP1348 ribC ribC hisE hisE pyrD pyrD taqD taqD cbiX(s) cbiX(s) arfB arfB pyrB pyrB MMP1580 MMP1580
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query proteins and first shell of interactors
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second shell of interactors
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textmining
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protein homology
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ribHRiboflavin synthase, beta subunit (6,7-dimethyl-8-ribityllumazine synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (137 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
 
 0.999
MMP1348
Conserved hypothetical protein; Belongs to the UPF0292 family.
 
 
 0.989
ribC
Riboflavin synthase.
 
 
  0.968
hisE
Phosphoribosyl-ATP pyrophosphatase; Citation: Kwon JH, Chun JY, Lee HS, Cheon CI, Song ES, Min KH, Lee MS.(2000) Can J Microbiol.46:848-55.
  
    0.944
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.896
taqD
Glycerol-3-phosphate cytidyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
  
  
 0.886
cbiX(s)
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
   
  
 0.823
arfB
Conserved hypothetical archeal protein; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
     
 0.818
pyrB
Aspartate carbamoyltransferase; Citation: J. Biol Chem 2000 May 26; 275 (21) 15820-7.
  
    0.798
MMP1580
Dihydropteroate synthase, DHPS:Dihydropteroate synthase-related protein synthase-related protein.
  
  
 0.785
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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