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hpt hpt MMP0418 MMP0418 purB purB guaA guaA guaA-2 guaA-2 surE surE hpcE hpcE apt apt MMP1534 MMP1534 adkA adkA purP purP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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hptHypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (185 aa)    
Predicted Functional Partners:
MMP0418
Carbohydrate kinase, PfkB; Belongs to the carbohydrate kinase PfkB family.
  
 0.978
purB
Adenylosuccinate lyase; Citation: Toth EA, Worby C, Dixon JE, Goedken ER, Marqusee S, Yeates TO. (2000) J Mol Biol 301:433-50; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.978
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 0.976
guaA-2
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.950
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
 
 0.936
hpcE
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase.
  
  
 0.915
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 
0.907
MMP1534
Conserved hypothetical protein.
   
 
 0.906
adkA
Adenylate kinase; Ferber DM, Haney PJ, Berk H, Lynn D, Konisky J. (1997) Gene 185:239-44; Citation: Rusnak P, Haney P, Konisky J. (1995) J Bacteriol 177:2977-81.
   
 
  0.904
purP
Conserved hypothetical archaeal protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family.
    
  0.903
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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