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thiC thiC MMP1639 MMP1639 thiE thiE MMP0655 MMP0655 thi4 thi4 MMP1234 MMP1234 thiM thiM purO purO purM-2 purM-2 purM purM purC purC
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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textmining
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protein homology
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thiCThiamine biosynthesis protein, putative; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (426 aa)    
Predicted Functional Partners:
MMP1639
Acyl-CoA dehydrogenase.
 
 
 0.999
thiE
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.997
MMP0655
Hypothetical protein.
  
  
 0.980
thi4
NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
  
  
 0.941
MMP1234
Conserved hypothetical membrane related protein.
 
  
 0.897
thiM
Hydroxyethylthiazole kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
  
 0.866
purO
IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
  
  
 0.851
purM-2
AIR synthase related protein:Phosphoribosylformylglycinamidine cyclo-ligase.
  
 
 0.843
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
    
  0.806
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Citation: Tiedeman AA, DeMarini DJ, Parker J, Smith JM. (1990) J Bacteriol 172:6035-41; Belongs to the SAICAR synthetase family.
     
 0.795
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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