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gldA gldA MMP0007 MMP0007 purD purD MMP1679 MMP1679 thiE thiE MMP0140 MMP0140 porD porD gapN gapN MMP1596 MMP1596 hemC hemC MMP0328 MMP0328
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gldAGlycerol dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (334 aa)    
Predicted Functional Partners:
MMP0007
Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
  
  
 0.975
purD
Phosphoribosylamine--glycine ligase; Citation: Kanai S, Toh H. (1999) J Mol Evol 48:482-92.
     
 0.858
MMP1679
Conserved hypothetical archeal protein; Belongs to the UPF0179 family.
 
  
 0.837
thiE
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
     
 0.829
MMP0140
Conserved hypothetical protein; HypF family; Citation: Mol. Microbiol. 8 (3); 471-481 (1993).
       0.827
porD
Pyruvate oxidoreductase (synthase) subunit delta; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8; Lin, WC et al, Arch Microbiol 179:444 (2003).
     
 0.826
gapN
Aldehyde dehydrogenase; Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate.
  
  
 0.820
MMP1596
Conserved Hypothetical Archael protein.
  
  
 0.815
hemC
Porphobilinogen deaminase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82.
     
 0.806
MMP0328
Conserved hypothetical protein; Predicted membrane protein.
     
 0.783
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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