node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMP0079 | pyrD | MMP0079 | MMP0439 | Orotate phosphoribosyltransferase related protein; Citation: Bitan-Banin G, Ortenberg R, Mevarech M. (2003) J Bacteriol 185:772-8; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.920 |
MMP0079 | pyrE | MMP0079 | MMP1492 | Orotate phosphoribosyltransferase related protein; Citation: Bitan-Banin G, Ortenberg R, Mevarech M. (2003) J Bacteriol 185:772-8; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.921 |
MMP0079 | pyrF | MMP0079 | MMP0602 | Orotate phosphoribosyltransferase related protein; Citation: Bitan-Banin G, Ortenberg R, Mevarech M. (2003) J Bacteriol 185:772-8; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.930 |
MMP0079 | pyrK | MMP0079 | MMP0919 | Orotate phosphoribosyltransferase related protein; Citation: Bitan-Banin G, Ortenberg R, Mevarech M. (2003) J Bacteriol 185:772-8; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 2Fe-2S Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:NADH:cytochrome b5 reductase (CBR); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.900 |
MMP0681 | carA | MMP0681 | MMP1589 | Xanthine/uracil permease family. | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | 0.986 |
MMP0681 | carB | MMP0681 | MMP1013 | Xanthine/uracil permease family. | Carbamoyl-phosphate synthase large chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarB family. | 0.978 |
MMP0681 | pyrB | MMP0681 | MMP1659 | Xanthine/uracil permease family. | Aspartate carbamoyltransferase; Citation: J. Biol Chem 2000 May 26; 275 (21) 15820-7. | 0.996 |
MMP0681 | pyrC | MMP0681 | MMP1009 | Xanthine/uracil permease family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.993 |
MMP0681 | pyrD | MMP0681 | MMP0439 | Xanthine/uracil permease family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.897 |
MMP0681 | pyrE | MMP0681 | MMP1492 | Xanthine/uracil permease family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.973 |
MMP0681 | pyrF | MMP0681 | MMP0602 | Xanthine/uracil permease family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.979 |
MMP0681 | pyrK | MMP0681 | MMP0919 | Xanthine/uracil permease family. | 2Fe-2S Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:NADH:cytochrome b5 reductase (CBR); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.837 |
MMP0681 | ribH | MMP0681 | MMP0050 | Xanthine/uracil permease family. | Riboflavin synthase, beta subunit (6,7-dimethyl-8-ribityllumazine synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.440 |
carA | MMP0681 | MMP1589 | MMP0681 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Xanthine/uracil permease family. | 0.986 |
carA | carB | MMP1589 | MMP1013 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarB family. | 0.999 |
carA | pyrB | MMP1589 | MMP1659 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Aspartate carbamoyltransferase; Citation: J. Biol Chem 2000 May 26; 275 (21) 15820-7. | 0.999 |
carA | pyrC | MMP1589 | MMP1009 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
carA | pyrD | MMP1589 | MMP0439 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.996 |
carA | pyrE | MMP1589 | MMP1492 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.994 |
carA | pyrF | MMP1589 | MMP0602 | Carbamoyl-phosphate synthase small chain; Citation: Nicoloff H, Hubert JC, Bringel F. (2000). J. Bacteriol. 182:3416-3422; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.993 |